Evolving paradigms in the treatment of opioid-induced bowel dysfunction

In conclusion, opioid antagonists restricted to the periphery show promising results, but use of different definitions and outcome measures complicate comparison. However, an international working group has recently suggested a consensus definition for opioid-induced constipation and relevant outcome measures have also been proposed. If investigators within this field adapt the suggested consensus and include symptoms related to dysfunction of the upper gut, it will ease comparison and be a step forward in future research.
Source: Therapeutic Advances in Gastroenterology - Category: Gastroenterology Authors: Tags: Reviews Source Type: research