Comparative bactericidal activity of four fluoroquinolones against Pseudomonas aeruginosa isolated from chronic suppurative otitis media
We examined bactericidal activity of four types of fluoroquinolones, garenoxacin (GRNX), levofloxacin (LVFX), ciprofloxacin (CPFX) and sitafloxacin (STFX) against current isolates of P. aeruginosa (50 strains).
Results:
STFX exhibited the most potent activity of both MIC
50
and MIC
90
, followed by CPFX, LVFX, and GRNX. The number of GRNX-resistant strains was significantly greater than those of LVFX, CPFX, and STFX (P
Source: BMC Ear, Nose and Throat Disorders - Category: ENT & OMF Authors: Katsuhisa IkedaShigeki MisawaTakeshi Kusunoki Source Type: research