Emerging role of Long Noncoding RNAs in lung cancer: current status and future prospects

Lung cancer is the leading cause of cancer-related death worldwide with a 5-year survival rate of less than 15%, despite significant advances in both diagnostic and therapeutic approaches. Combined genomic and transcriptomic sequencing studies have identified numerous genetic driver mutations that are responsible for the development of lung cancer. Importantly, these approaches have also uncovered the widespread expression of “noncoding RNAs” including long noncoding RNAs (LncRNAs), which impact biologic responses through the regulation of mRNA transcription or translation.
Source: Respiratory Medicine CME - Category: Respiratory Medicine Authors: Tags: Review article Source Type: research