Anxiety on Orkambi?

Hello all- I was wondering if anyone else on an anti-depressant or anxiety medication is experiencing anxiety or mood cycling on Orkambi? I am prescribed 10mg of escilatopram (Lexapro) for generalized anxiety, and have not had issues for years. However, I noticed within the first week that I have had extreme issues with anxiety attacks, constantly feeling nervous or jittery, and mood swings. I understand that there is a moderate interaction there, but it almost feels as if I went 'cold turkey' off my meds, and I even experienced minor brain zaps one morning. I tried doubling my dosage for one week (taking 1 20mg pill instead of 1/2), to no avail besides feeling moderately sedated. Has anyone else on an SSRI experienced these issues? Has anyone found solutions that either revolve around switching medications, or for instance, taking their SSRIs at a different time of day? I am working with the CF social worker and also my primary care physician, but I wanted to hear about others' experiences. I can take the other side effects- nausea, fatigue, or overheating but the extra anxiety is almost enough for me to call it quits. Thanks in advance!
Source: Cystic Fibrosis Adults Forum - Category: Respiratory Medicine Authors: Tags: Adults Source Type: forums