Hypoxia mediated pulmonary edema: potential influence of oxidative stress, sympathetic activation and cerebral blood flow

Conclusion:
Cerebral hypoxia, with systemic normoxia, is not systematically associated with an increase in oxidative stress and compensatory antioxidant enzymes in lung, suggesting oxidative stress did not contribute to NPE in lung. However, increased SNS activity may play a role in the induction of NPE during hypoxia.

Source: BMC Physiology - October 9, 2015 Category: Physiology Authors: Shadi KhademiMelinda FryeKimberly JeckelThies SchroederEric MonnetDave IrwinPatricia ColeChristopher BellBenjamin MillerKaryn Hamilton Source Type: research