Clinical Trials Exploring the benefit of immunotherapy and radiation in Cancer treatment: A review of the past and A look into the future

Cancer immunotherapy is rapidly redefining the standard of cancer care. The role of radiation therapy in eliciting anti-tumoral immune response is also being actively investigated in combination with various immunotherapeutic agents to exploit potential synergy between the two modalities. In this review, we summarize the rationale and results of past and on-going clinical trials that combined the use of radiation therapy and immunogenic agents such as vaccines, cytokines, immune checkpoint inhibitors, co-stimulatory agonists, and myeloid activators.
Source: Current Problems in Cancer - Category: Cancer & Oncology Authors: Source Type: research