Systematic review of case reports on the abscopal effect

Radiation therapy is a highly effective local treatment for cancer. However, sporadic events of tumor regression in un-irradiated fields, known as abscopal effect, have been observed for decades. This abscopal effect has more recently been postulated to be a result of anti-tumor immune response induced by radiation therapy. With the advent of modern immunotherapy, the potential for immune activation by radiation therapy defines a novel role for radiation therapy in systemic disease. In this context, we have searched documented cases abscopal effect of radiation therapy in literature.
Source: Current Problems in Cancer - Category: Cancer & Oncology Authors: Source Type: research