Glucagon Increases Energy Expenditure Independently of Brown Adipose Tissue Activation in Humans.

CONCLUSIONS: Glucagon increases energy expenditure to a similar magnitude compared to cold activation, but independently of BAT thermogenesis. This finding is of importance for the development of safe treatments of obesity through upregulation of energy expenditure.
PMID: 26434748 [PubMed - as supplied by publisher]

Source: Diabetes Metab - October 5, 2015 Category: Endocrinology Authors: Salem V, Izzi-Engbeaya C, Coello C, Thomas DB, Chambers ES, Comninos A, Buckley A, Win Z, Al-Nahhas A, Rabiner EA, Gunn RN, Bloom SR, Tan TM, Dhillo WS Tags: Diabetes Obes Metab Source Type: research