Prophylactic salpingectomy and prophylactic salpingoophorectomy for adnexal high-grade serous epithelial carcinoma: A reappraisal

At present, there is no effective screening of ovarian cancer. Primary prevention may be the only strategy to decrease the mortality from ovarian cancer, not only in women at high risk but also at low risk.Several recent studies have identified the distal fimbriae end of the fallopian tubes as primary precursor of High-grade serous carcinoma. Serous tubal intraepithelial carcinomas and occult invasive serous carcinomas have been identified in 2-17% of the fallopian tubes of BRCA 1/2 positive women undergoing risk-reducing salpingo-oophorectomy.

Source: Surgical Oncology - October 7, 2015 Category: Surgery Authors: M.Reyes Oliver Perez, Javier Magriñá, Alvaro Tejerizo García, Jesus Salvador Jiménez Lopez Source Type: research