Resveratrol Stimulates Hydrogen Sulfide (H2S) Formation to Relax Murine Corpus Cavernosum

ConclusionsThese results demonstrate that RVT‐induced relaxation is at least partly dependent on H2S formation and acts independent of eNOS pathway. In phosphodiesterase 5 inhibitor (PDE‐5i) nonresponder population, combination therapy with RVT may reverse erectile dysfunction via stimulating endogenous H2S formation. Yetik‐Anacak G, Dereli MV, Sevin G, Ozzayım O, Erac Y, and Ahmed A. Resveratrol stimulates hydrogen sulfide (H2S) formation to relax murine corpus cavernosum. J Sex Med **;**:**–**.

Source: The Journal of Sexual Medicine - October 6, 2015 Category: Sexual Medicine Authors: Gunay Yetik‐Anacak, Mehmet V. Dereli, Gulnur Sevin, Ozge Ozzayım, Yasemin Erac, Asif Ahmed Tags: Original Research Source Type: research