Abstract A59: Dietary tomato and lycopene inhibition of prostate carcinogenesis in the TRAMP Model is {beta},{beta}-carotene 9',10'-oxygenase (BCO2)-dependent

Conclusions: Overall, dietary tomato and lycopene inhibited the progression of prostate cancer in TRAMP in a BCO2-dependent manner. Future human studies to examine the role of lycopene metabolism and BCO2 genotype in cancer risk reduction are warranted.Citation Format: Hsueh-Li Tan, Jennifer M. Thomas-Ahner, Nancy E. Moran, Gregory S. Young, John W. Erdman, Jr., Steven K. Clinton. Dietary tomato and lycopene inhibition of prostate carcinogenesis in the TRAMP Model is β,β-carotene 9',10'-oxygenase (BCO2)-dependent. [abstract]. In: Proceedings of the Thirteenth Annual AACR International Conference on Frontiers in Cancer Prevention Research; 2014 Sep 27-Oct 1; New Orleans, LA. Philadelphia (PA): AACR; Can Prev Res 2015;8(10 Suppl): Abstract nr A59.

Source: Cancer Prevention Research - October 2, 2015 Category: Cancer & Oncology Authors: Tan, H.-L., Thomas-Ahner, J. M., Moran, N. E., Young, G. S., Erdman, J. W., Clinton, S. K. Tags: Pediatric Malignancies: Poster Presentations - Proffered Abstracts Source Type: research