SIRT1-related inhibition of pro-inflammatory responses and oxidative stress are involved in the mechanism of nonspecific low back pain relief after exercise through modulation of Toll-like receptor 4

This study demonstrates that exercise intervention improves low back pain symptoms through regulation of the SIRT1 axis with repression of oxidative stress and TLR-4 inhibition.

Source: Journal of Biochemistry - September 29, 2015 Category: Biochemistry Authors: Cheng, Y.-Y., Kao, C.-L., Ma, H.-I., Hung, C.-H., Wang, C.-T., Liu, D.-H., Chen, P.-Y., Tsai, K.-L. Tags: Regular Papers Source Type: research