Effect of Botanical Immunomodulators on Human CYP3A4 Inhibition: Implications for Concurrent Use as Adjuvants in Cancer Therapy

Conclusion. Our findings suggest that constituents of TCE extract especially protoberberine alkaloids have the potential to interact with cancer chemotherapy agents that are metabolized by CYP3A4 in vivo.

Source: Integrative Cancer Therapies - February 19, 2014 Category: Cancer & Oncology Authors: Patil, D., Gautam, M., Gairola, S., Jadhav, S., Patwardhan, B. Tags: Articles Source Type: research