MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice

ConclusionDeficiency of the MTHFD1 10‐formyltetrahydrofolate synthetase activity in embryos is associated with increased incidence of congenital heart defects. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc.

Source: Birth Defects Research Part A: Clinical and Molecular Teratology - September 26, 2015 Category: Perinatology & Neonatology Authors: Karen E. Christensen, Liyuan Deng, Renata H. Bahous, Loydie A. Jerome‐Majewska, Rima Rozen Tags: Original Research Article Source Type: research