Chromium, zinc and magnesium status in type 1 diabetes.

Chromium, zinc and magnesium status in type 1 diabetes.
Curr Opin Clin Nutr Metab Care. 2015 Sep 24;
Authors: Lin CC, Huang YL
Abstract
PURPOSE OF REVIEW: Chromium, zinc, and magnesium are involved in insulin signal transduction, glucose metabolism, and cellular antioxidative defense. This review details the statuses of chromium, zinc, and magnesium in type 1 diabetes patients.
RECENT FINDINGS: Blood levels of trace elements (especially magnesium and zinc) were lower in type 1 diabetes patients than in controls and were even lower in type 1 diabetes patients with poor glycemic control. Studies with mouse models have shown that chromium and magnesium supplementation alleviated diabetes-induced complications and improved glycemic control.
SUMMARY: Many studies indicated positive correlations between decreased levels of serum chromium, zinc, and magnesium and poor glycemic control. The supplementation of type 1 diabetes patients with zinc, magnesium, and chromium may help to control diabetes and prevent diabetes-related oxidative injuries, but require further study.
PMID: 26406393 [PubMed - as supplied by publisher]

Source: Diabetes Metab - September 24, 2015 Category: Endocrinology Authors: Lin CC, Huang YL Tags: Curr Opin Clin Nutr Metab Care Source Type: research