Detection of a PDGFRB fusion in refractory CMML without eosinophilia: A case for broad spectrum tumor profiling

Publication date: Available online 24 September 2015 Source:Leukemia Research Reports Author(s): Gillian C. Bell, Eric Padron In this case report, we describe a refractory CMML case without eosinophilia harboring a PDGFRB rearrangement leading to a favorable response with imatinib. We believe this case demonstrates the utility of broad spectrum genomic profiling in refractory CMML cases as an opportunity to uncover additional treatment options.

Source: Leukemia Research Reports - September 25, 2015 Category: Hematology Source Type: research