Sirolimus for refractory autoimmune hemolytic anemia after allogeneic hematopoietic stem cell transplantation: a case report and literature review of the treatment of post-transplant autoimmune hemolytic anemia

We present a pediatric patient with refractory AIHA after umbilical cord blood transplantation (UCBT). She developed severe AIHA at 3 months after transplantation and was unresponsive to multiple treatment modalities, including corticosteroids, intravenous immunoglobulin, plasma exchange and rituximab, resulting in persistent transfusion dependency.

Source: Transfusion Medicine Reviews - September 25, 2015 Category: Hematology Authors: Jeong A. Park, Hyun Hee Lee, Hyun-Seop Kwon, Chung-Ryul Baik, Sae-Am Song, Jung Nye Lee Source Type: research