The Effect of Dofetilide on the Heart Rate of GD11 and GD13 Rat Embryos, in vivo, Using Ultrasound

CONCLUSIONSUltrasound is a useful technique to investigate the effect of maternally administered drugs on the embryonic HR in the rat. The results may provide more information about the safety of these drugs in pregnancy leading to better risk assessment for the human

Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology - August 1, 2015 Category: Perinatology & Neonatology Authors: Helen Ritchie, Diana Oakes, Tzong‐tyng Hung, Elizabeth Hegedus, Shreya Sood, William Webster Tags: Research Article Source Type: research