Clinical applications of advanced lipoprotein testing in diabetes mellitus.

Clinical applications of advanced lipoprotein testing in diabetes mellitus. Clin Lipidol. 2011 Aug 1;6(4):371-387 Authors: Moin DS, Rohatgi A Abstract Traditional lipid profiles often fail to fully explain the elevated cardiovascular risk of individuals with diabetes mellitus. Advanced lipoprotein testing offers a novel means to evaluate dyslipidemia and refine risk estimation. Numerous observational studies have demonstrated a characteristic pattern of elevated levels of small, dense LDL particles, out of proportion to traditional lipid levels, in patients with both diabetes mellitus and the metabolic syndrome. Commonly used glucose and lipid-lowering agents have varied effects in patients with diabetes on both LDL and HDL subfractions. The exact role of advanced lipoprotein testing in patients with diabetes mellitus and the metabolic syndrome remains unclear but may offer improved assessment of cardiovascular risk compared with traditional lipid measurements. PMID: 22162979 [PubMed - as supplied by publisher]
Source: Clinical Lipidology - Category: Lipidology Tags: Clin Lipidol Source Type: research