Corticosteroids in IgA Nephropathy: A Retrospective Analysis from the VALIGA Study

This retrospective study assessed 1147 patients with IgA nephropathy from the European Validation Study of the Oxford Classification of IgAN (VALIGA) cohort.  From this group as well a propensity matched cohort, the authors concluded that corticosteroids reduced proteinuria and the rate of renal function decline and increased renal survival even in patients with an eGFR < 50 ml/min compared to renin angiotensin system blockade alone.  Furthermore, the benefits were proportionate to the level of proteinuria. : Proteinuria: Is the ONTARGET renal substudy actually off target? Moderate dietary sodium restriction added to angiotensin converting enzyme inhibition compared with dual blockade in lowering proteinuria and blood pressure: randomised controlled trial Preserving residual renal function in peritoneal dialysis: volume or biocompatibility?
Source: Nephrology Now - Category: Urology & Nephrology Authors: Tags: Chronic Kidney Disease Glomerulonephritis Source Type: research