Long‐term glycemic control with hepatic insulin gene therapy in streptozotocin‐diabetic mice

ConclusionsOur studies demonstrate the possibility for long‐term glycemic correction following AAV‐mediated HIGT in mice. However, the dose–response relationship is irregular, and metabolic responsiveness may be less than that observed in rats. Copyright © 2015 John Wiley & Sons, Ltd.

Source: The Journal of Gene Medicine - September 17, 2015 Category: Genetics & Stem Cells Authors: Peter M. Thulé, Adam G. Campbell, Dingwu Jia, Yulin Lin, Shou You, Sara Paveglio, Darin E. Olson, Miroslaw Kozlowski Tags: Research Article Source Type: research