Prominent Vascular and Perivascular Eosinophilic Infiltrates Heralding CNS Mycosis Fungoides

This study reports a patient with known cutaneous MF (under treatment) who presented with a CNS syndrome and multiple brain lesions. Brain biopsy demonstrated massive eosinophilic infiltrates but no MF cells. Despite treatment, new lesions developed and the patient died. At autopsy, there was massive involvement MF cells, suggesting that the eosinophilic infiltrates presaged the severe involvement of the CNS by MF.
Source: Journal of Neuropathology and Experimental Neurology - Category: Neurology Tags: Brief Report Source Type: research