[11C]raclopride binding in the striatum of minimally restrained and free‐walking awake mice in a positron emission tomography study

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We developed an experimental system enabling PET imaging of free‐walking awake mice. [11C]raclopride‐PET images suggest that our system avoids of the effects of anesthesia and alleviates restraint stress in animal PET studies while measuring the characteristics of neurotransmission components.

Source: Synapse - September 11, 2015 Category: Neurology Authors: Hiroyuki Takuwa, Jun Maeda, Yoko Ikoma, Masaki Tokunaga, Hidekatsu Wakizaka, Shouko Uchida, Iwao Kanno, Junko Taniguchi, Hiroshi Ito, Makoto Higuchi Tags: Research Article Source Type: research