Mechanistic-enriched models: integrating transcription factor networks and metabolic deregulation in cancer

Conclusion: After analyzing the way we studied the coupling of metabolic and transcriptional deregulation in breast cancer, we have concluded that one plausible strategy to integrate data driven and hypothesis driven approaches is by means of resorting to fundamental and well established laws of physics and chemistry since these provide a solid ground for assessment.
Source: Theoretical Biology and Medical Modelling - Category: Biomedical Science Authors: Source Type: research