Benign Soft Tissue Lesions That May Mimic Malignancy

Imitations of malignancy are abundant in the arena of soft tissue pathology, and can represent a significant diagnostic challenge for clinicians, radiologists, and pathologists alike. Not only may benign conditions mimic malignancy, but focal areas of malignant entities may mimic benignancy. Clinically these pseudoneoplastic lesions may simulate a sarcoma as a mass forming lesion, in some cases with aggressive local behavior and rapid growth, which is worrisome to the patient and clinician. Histologically, benign soft tissue neoplasms may have microscopic features overlapping with malignant soft tissue tumors, namely increased cellularity, nuclear pleomorphism, spindle cell growth, and infiltrative growth.
Source: Seminars in Diagnostic Pathology - Category: Pathology Authors: Source Type: research