Interleukin-23p19 expression in patients with ulcerative colitis and its relation to disease severity

Conclusion Increased expression of the IL-23p19 gene has a role in the pathogenesis of ulcerative colitis. Targeted therapy directed against IL-23p19 may be effective in its treatment. Increased expression of the IL-23p19 gene and IL-23R with high serum IL-23 is correlated positively with disease severity.
Source: Advances in Digestive Medicine - Category: Gastroenterology Source Type: research