Polymorphisms within angiotensin II receptor type 1 gene associated with essential hypertension in Chinese Hani and Yi minorities

Conclusion:
Our findings suggest that rs387967 is associated with the susceptibility to essential hypertension in a Yi population and the tendency was replicated in systolic blood pressure and diastolic blood pressure detection. Meta-analysis revealed that C allele of rs2638360 could significantly increase the risk of essential hypertension. The two single nucleotide polymorphisms maybe play a role in the pathology of essential hypertension.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - September 7, 2015 Category: Biomedical Science Authors: Yang, H., Bai, S., Wu, Y., Li, Q., Luo, F., Li, B., Jin, Y., Xiao, C. Tags: Original Articles Source Type: research