Angiotensin IV and the human esophageal mucosa: An exploratory study in healthy subjects and gastroesophageal reflux disease patients

Conclusion:
The AT4R and formation enzymes of AngIII and AngIV are present in the human esophageal epithelium. Moreover, the present results suggest that AngIV exert regulatory impact on the epithelium and that RAS is involved in mucosal aberrations associated with GERD.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - September 7, 2015 Category: Biomedical Science Authors: Bjorkman, E., Edebo, A., Fandriks, L., Casselbrant, A. Tags: Original Articles Source Type: research