Tissue IGF-I measured by microdialysis reflect body glucose utilization after rhIGF-I injection in type 1 diabetes.

CONCLUSION: We demonstrate that md-IGF-I measurements are valid and physiologically relevant by reflecting rhIGF-I induced glucose uptake. Future studies should elucidate the role of local tissue IGF-I in diabetic vascular complications. PMID: 26331550 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26331550?dopt=Abstract

Source: Diabetes Metab - September 2, 2015 Category: Endocrinology Authors: Ekström K, Pulkkinen MA, Carlsson-Skwirut C, Brorsson AL, Ma Z, Frystyk J, Bang P Tags: J Clin Endocrinol Metab Source Type: research