Double marker test and uterine Doppler in cases with hyperemesis gravidarum

This study was conducted to evaluate the possible relationship between double marker test (serum β-hCG, PAPP-A) and uterine artery Doppler indices in cases with hyperemesis gravidarum at 11–13 weeks of gestation in 60 patients admitted to El-Shatby Maternity University Hospital. Patients and methods: Patients were divided into two groups: the study group included those diagnosed with hyperemesis gravidarum and the control group included those with normal uncomplicated first trimester pregnancy. Our study concluded that testing for serum levels of β-hCG and PAPP-A in cases of hyperemesis gravidarum showed insignificant difference compared with normal gestation cases and is not recommended for routine clinical practice. Results and conclusion: Our study also concluded that Doppler indices for blood flow in uterine arteries showed insignificant difference between cases of hyperemesis gravidarum and normal gestation cases, thereby signifying that hyperemesis gravidarum is not a risk factor for the development of preeclampsia or intrauterine growth restriction later during pregnancy.
Source: Journal of Evidence-Based Women’s Health Journal Society - Category: OBGYN Tags: Original articles Source Type: research