Reduced Effect of Aspirin and Clopidogrel Following Hybrid Coronary Revascularization

Conclusions: A transient reduction in the antiplatelet effect of aspirin and clopidogrel was observed after hybrid coronary revascularization despite limited surgical trauma and off-pump technique. Neither baseline platelet aggregation nor postoperatively increased platelet turnover and acute-phase response could explain this finding. ClinicalTrials.gov identifier, NCT02293928.

http://cat.sagepub.com/cgi/content/abstract/21/7/603?rss=1

Source: Clinical and Applied Thrombosis/Hemostasis - September 2, 2015 Category: Hematology Authors: Modrau, I. S., Wurtz, M., Kristensen, S. D., Hvas, A.-M. Tags: Original Articles Source Type: research