Non-rigid Image Registration with Anatomical Structure Constraint for Assessing Locoregional Therapy of Hepatocellular Carcinoma

Locoregional therapy (LT) is a choice for the treatment of hepatocellular carcinoma (HCC). It targets the specific inflicted region of the liver by injecting a higher dose of drugs into the tumor without exposing the rest of the patient's body. This therapy reduces the chances of infection and shortens recovery time. However, in certain situations, tumors cannot be removed clearly with LT. Thus, it is desirable to assess the therapeutic efficiency after treatment of HCC. Currently, the assessment method widely used compares the two-dimensional (2D) CT images (axial, coronal, and sagittal) manually; however, selecting the corresponding slices is a time-consuming process.

Source: Computerized Medical Imaging and Graphics - August 20, 2015 Category: Radiology Authors: Chunhua Dong, Toshihito Seki, Ryosuke Inoguchi, Chen-Lun Lin, Xian-hua Han, Yen-wei Chen Source Type: research