The diagnostic utility of antibodies to smoothelin and desmin in staging of urothelial carcinoma

Conclusion: The relatively distinct immunohistochemical staining pattern of smoothelin between MP and MM (including its hyperplastic forms) makes it a robust and attractive marker to be incorporated into the contemporary diagnostic armamentarium for the sometimes difficult area of staging bladder urothelial carcinoma. It also confirmed the use of desmin to differentiate between smooth muscle cells (whether MM or MP) and proliferating myofibroblasts.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research