RNAi Screening with Self-Delivering, Synthetic siRNAs for Identification of Genes That Regulate Primary Human T Cell Migration

This study therefore demonstrates the ease and benefits of conducting siRNA library screens in primary human T cells using self-delivering, chemically modified siRNAs, and it emphasizes the feasibility and potential of this approach for elucidating the signaling pathways that regulate T cell function.

Source: Journal of Biomolecular Screening - August 19, 2015 Category: Molecular Biology Authors: Freeley, M., Derrick, E., Dempsey, E., Hoff, A., Davies, A., Leake, D., Vermeulen, A., Kelleher, D., Long, A. Tags: Articles Source Type: research