Leptin produced by obese adipose stromal/stem cells enhances proliferation and metastasis of estrogen receptor positive breast cancers

Conclusion:
This study provides mechanistic insight as to how obesity enhances the proliferation and metastasis of breast cancer cells; specifically, obASC-derived leptin contributes to the aggressiveness of breast cancer in obese women.

Source: Breast Cancer Research - August 19, 2015 Category: Cancer & Oncology Authors: Amy StrongJason OhlsteinBrandi BiagasLyndsay RhodesDorothy PeiH. TuckerClaire LlamasAnnie BowlesMaria DutreilShijia ZhangJeffrey GimbleMatthew BurowBruce Bunnell Source Type: research