Recruitment of dorsal midbrain catecholaminergic pathways in the recovery from nerve injury evoked disabilities
Conclusions:
Our data provide evidence for: (1) potential increases in dopamine and noradrenaline synthesis in vPAG cells; and (2) increased catecholaminergic drive on vPAG neurons in rats in which transient changes in social behavior are seen following CCI. The data suggests a role for dopaminergic and noradrenergic outputs, and catecholaminergic inputs of the vPAG in the expression of one of the profiles of behavioural and endocrine change triggered by nerve injury.
Source: Molecular Pain - Category: Molecular Biology Authors: David MorJames KangPeter WyllieVignaraja ThirunavukarasuHayden HoultonPaul AustinKevin Keay Source Type: research
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