Abundance and Localization of Progesterone Receptor Isoforms in Endometrium in Women With and Without Endometriosis and in Peritoneal and Ovarian Endometriotic Implants

Conclusions:
Endometriotic lesions and eutopic endometrium from women with endometriosis are uniform in a PR-A-dominant state. The data suggest that menstrual efflux of a PR-A-dominant endometrial tissue into the peritoneal cavity may play a role in the pathophysiology of endometriosis.

Source: Reproductive Sciences - August 10, 2015 Category: Reproduction Medicine Authors: Bedaiwy, M. A., Dahoud, W., Skomorovska-Prokvolit, Y., Yi, L., Liu, J. H., Falcone, T., Hurd, W. W., Mesiano, S. Tags: Original Articles Source Type: research