The molecular landscape of premenopausal breast cancer
Conclusion:
Together these data suggest that ER+ preM tumors have distinct molecular characteristics compared to ER+ postM tumors, particularly with respect to integrin/laminin and EGFR signaling, which may represent therapeutic targets in this subgroup of breast cancers.
Source: Breast Cancer Research - Category: Cancer & Oncology Authors: Serena LiaoRyan HartmaierKandace McGuireShannon PuhallaSoumya LuthraUma ChandranTianzhou MaRohit BhargavaFrancesmary ModugnoNancy DavidsonSteve BenzAdrian LeeGeorge TsengSteffi Oesterreich Source Type: research
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