The ONCOTYROL Prostate Cancer Outcome and Policy Model: Effect of Prevalence Assumptions on the Benefit-Harm Balance of Screening

Conclusions. Our calibration suggests that not all cancers are at risk of progression, and screening sensitivity may be lower at older ages. PCa screening models that use calibration to simulate disease progression in the unobservable latent phase are highly sensitive to prevalence assumptions.

Source: Medical Decision Making - August 1, 2015 Category: Health Management Authors: Muhlberger, N., Kurzthaler, C., Iskandar, R., Krahn, M. D., Bremner, K. E., Oberaigner, W., Klocker, H., Horninger, W., Conrads-Frank, A., Sroczynski, G., Siebert, U. Tags: Original Articles Source Type: research