Recombinant Human Erythropoietin Protects Myocardial Cells from Apoptosis Via the JAK2/STAT5 Pathway in Rats with Epilepsy

Conclusions These results indicate that myocardial cell apoptosis may contribute to myocardial injury in epilepsy. EPO protects myocardial cells from apoptosis via the JAK2/STAT5 pathway in rats with experimental epilepsy, whereas CEPO exerts anti-apoptotic activity perhaps via a pathway independent of JAK2/STAT5 signaling.
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research