Iron‐loaded PLLA nanoparticles as highly efficient intracellular markers for visualization of mesenchymal stromal cells by MRI

In conclusion the presented work demonstrates the applicability of iPLLA particles as efficient intracellular marker for MSC labeling for monitoring the fate of the cells by MRI. Copyright © 2014 John Wiley & Sons, Ltd.
High R2* relaxivity rate of nanometer‐sized iPLLA enables visualization of a single labelled cell in vitro and allows sensitive in vivo and detection of local cell aggregations at a relatively low payload of MR contrast.

Source: Contrast Media and Molecular Imaging - February 12, 2014 Category: Radiology Authors: I. Vernikouskaya, N. Fekete, M. Bannwarth, A. Erle, M. Rojewski, K. Landfester, G. Schmidtke‐Schrezenmeier, H. Schrezenmeier, V. Rasche Tags: Full Paper Source Type: research