Muscle transcriptome response to ACTH administration in a free-ranging marine mammal

This study represents one of the first transcriptome analyses of cellular responses to hypothalamic-pituitary-adrenal axis stimulation in a free-living marine mammal and suggests that compensatory, tissue-sparing mechanisms may enable marine mammals to maintain cortisol and aldosterone sensitivity while avoiding deleterious long-term consequences of stress.

Source: Physiological Genomics - August 1, 2015 Category: Genetics & Stem Cells Authors: Khudyakov, J. I., Champagne, C. D., Preeyanon, L., Ortiz, R. M., Crocker, D. E. Tags: General Interest Source Type: research