Menace d’accouchement prématuré : reproductibilité du test de détection de la PAMG-1 avant, puis après toucher vaginal et cervicométrie

Conclusion Une prise en charge initiale ayant recours au test de détection de la PAMG-1 pourrait permettre de diminuer le taux d’hospitalisation inutile en ciblant plus précisément les patientes à fort risque d’accouchement prématuré. Objectives With current diagnostic resources, it is impossible to predict if a patient consulting in the obstetrics emergencies with symptoms of preterm labor, preterm delivery or not. A novel test for the detection of time to spontaneous preterm delivery was developed and would predict imminent delivery in 7 or 14 days from the time of testing. The diagnostic performances of detection test of PAMG-1 have been validated before digital examination. However digital examination is usually made in first line. The objective of this study was to assess the reproducibility of these diagnostic performances after digital examination and transvaginal ultrasound cervical length. Methods A prospective and observational study was conducted in a level 3 maternity (University Hospital of Saint-Etienne), from June 2013 to January 2014. Patients consulted in the obstetrics emergencies for threatened preterm birth between 24–34 weeks were enrolled with written and signed consent. Reproducibility of this test was assessed after digital examination, transvaginal ultrasound cervical length and a long time after all investigations. Results Forty-one patients were included in our study. Average gestational age was 29 weeks, digital examination was c...
Source: Gynecologie Obstetrique and Fertilite - Category: OBGYN Source Type: research