Potential role for GnRH in the synchronization of follicular emergence prior to the Superovulatory Day 0 protocol

The ability of GnRH to synchronize ovulation and new follicular wave emergence prior to a “Superovulatory Day 0” protocol was assessed in Santa Inês ewes. For oestrus synchronization, a 60-mg medroxyprogesterone acetate sponge was inserted for 6 d. One day before sponge removal, 37.5 μg d-cloprostenol and 300 IU eCG were injected i.m. After sponge removal, ewes were assigned to the following 3 groups: 1) GC – 1 mL saline at 12 h (n = 10), 2) G24h – 0.025 mg lecirelin (GnRH agonist) i.m. at 24 h (n = 10), or 3) G36h – 0.025 mg lecirelin i.m.

Source: Domestic Animal Endocrinology - July 31, 2015 Category: Endocrinology Authors: M.F.A. Balaro, J.F. Fonseca, T.G.B. Barbosa, J.M.G. Souza-Fabjan, L.M. Figueira, T.A. Teixeira, L.R. Carvalheira, F.Z. Brandão Source Type: research