Basal cell carcinoma: Epidemiology, clinical and histologic features, and basic science overview

Basal cell carcinoma (BCC) is a quite ubiquitous entity in dermatology and dermatopathology, and, together with cutaneous squamous cell carcinoma (cSCC), constitutes the bulk of the so-called “nonmelanoma skin cancer” (NMSC) cases. Both BCC and cSCC arise in a similar clinical background of chronic sun damage and immunosuppression, among other risk factors. However, it is important to emphasize that BCC represents more of a locally aggressive tumor that rarely metastasizes, compared with cSCC, particularly some subtypes, which may have a higher risk of metastatic spread and even death.
Source: Current Problems in Cancer - Category: Cancer & Oncology Authors: Source Type: research