Subtotal hepatectomy in swine for studying small‐for‐size syndrome and portal inflow modulation: is it reliable?

ConclusionsSubtotal hepatectomy of 90% in swine is a reliable model for SFSS inducing a significant increase in HVPG. However, in view of the relevant differences between swine and human splanchnic anatomy, this model is inadequate for studying the effects of PIM by SAL and splenectomy.

Source: HPB: official journal of the International Hepato Pancreat Biliary Association - July 30, 2015 Category: Gastroenterology Authors: Benjamin Darnis, Kayvan Mohkam, Zoé Schmitt, Stanislas Ledochowski, Jean‐Paul Vial, Serge Duperret, Catherine Vogt, Hassan Demian, Nicolas Golse, Salim Mezoughi, Christian Ducerf, Jean‐Yves Mabrut Tags: Original Article Source Type: research