Prevalence of pathogenicity island markers genes in uropathogenic Escherichia coli isolated from patients with urinary tract infectious

Conclusions Pathogenicity island markers cause horizontal transfer of genes. Many virulence genes are present in the pathogenicity islands regions in such a way that by deletion and/or mutation of these genes, the bacteria would lose its pathogenicity. Knowledge of the molecular details of uropathogenic E. coli is useful to develop successful strategies for the treatment of urinary tract infection and complications associated with urinary tract infections in human.
Source: Asian Pacific Journal of Tropical Disease - Category: Tropical Medicine Source Type: research