Ovarian and hormonal responses to single or continuous peripheral administration of senktide, a neurokinin 3 receptor agonist, during the follicular phase in goats

The present study aimed to investigate the effects of single or continuous administration of a neurokinin 3 receptor agonist, senktide, on hormonal and follicular dynamics in follicular-phase goats. Goats were injected with PGF2α in the luteal phase, and treated with an intravaginal progesterone device for 10 d. At 12 h after the cessation of progesterone treatment, the goats received a single i.v. injection of senktide (200 nmol, n = 4) or vehicle (n = 4), or continuous i.v. infusion of senktide (20 nmol/min, n = 6) or vehicle (n = 6) for 6 h.
Source: Domestic Animal Endocrinology - Category: Endocrinology Authors: Source Type: research