Potent immunotherapy against well‐established thymoma using adoptively transferred transgene IL‐6‐engineered dendritic cell‐stimulated CD8+ T‐cells with prolonged survival and enhanced cytotoxicity

ConclusionsOur data suggest that AdVIL‐6‐transfected DC‐stimulated CD8+ T cells with potent cytotoxicity and survival advantage may serve as an effective adoptive CD8+ T‐cell immunotherapy strategy for anti‐tumor treatment. This article is protected by copyright. All rights reserved.

Source: The Journal of Gene Medicine - June 1, 2015 Category: Genetics & Stem Cells Authors: Kalpana Kalyanasundaram Bhanumathy, Bei Zhang, Yufeng Xie, Aizhang Xu, Xin Tan, Jim Xiang Tags: Research Article Source Type: research