Serum sEPCR Levels Are Elevated in Patients With Alzheimer's Disease

In this study, we found that serum sEPCR levels were significantly increased in patients with AD when compared to control participants (P = .0005). There was no significant difference between patients with mild cognitive impairment (MCI) and healthy controls (P = .055) or between patients with AD and MCI (P = .054). Importantly, our results also indicate that the degree of cognitive impairment is significantly correlated with serum sEPCR levels in all patients and healthy controls. These findings suggest that serum sEPCR levels could be a potential candidate for a biomarker panel for AD diagnosis.
Source: American Journal of Alzheimer's Disease and Other Dementias - Category: Geriatrics Authors: Tags: Current Topics in Research Source Type: research